Lymedisease is a tick-borne illness caused by the spirochete B burgdorferi. Lymedisease can be divided into early disease (stage 1, EM), disseminated infection (stage 2), and late disease (stage 3, persistent infection). The first stage involves the skin, followed by stages 2 and 3, which often affect the skin, joints, CNS, and heart. However, any of the stages may fail to appear or may overlap with one another
|Localized erythema chronicum migrans||Early infection|
|Disseminated infection||Within days or years|
|Persistent infection||Months to years|
Lyme disease is a bacterial disease caused by Borrelia burgdorferi. The bacterium is transmitted to humans via a tick bite. Within 1 to 2 weeks after being infected, a “bull’s-eye” rash can develop at the tick bite site accompanied by fever, headache, and muscle or joint pain. Some people may have Lymedisease and not have any early symptoms. However, others can have a fever and other “flu-like” symptoms without a rash.
Most patients treated promptly with an appropriate antibiotic have an uncomplicated course. True failures are rare, and in most cases re-treatment or prolonged treatment is the result of misdiagnosis and misinterpretation of serologic results rather than inadequate therapy.