Lyme Disease Update Review
Information on lyme disease symptoms,sign,diagnosis,treatment and complication.This is an infectious disease caused by ticks infected with Borrelia burgdorferi.
Lyme Disease Microbiology
Microbiology. Of spirochetes in the Borrelia genus, B burgdorferi is the longest and narrowest , and has the fewest flagella. This organism can be grown from skin biopsy and other specimens on an artificial medium called Barbour-Stoenner-Kelly at 33 C. The B burgdorferi surface membrane is studded with lipoproteins called outer-surface proteins (OSPs) A, B, C, D, E, and F; other prominent flagellar antigens include flagellar protein, heat shock protein, and protoplasmic cylinder antigen. B burgdorferi is capable of altering its surface lipoproteins by recombining gene cassettes in a manner that resembles the mechanism of antigenic variation among the relapsing fever borreliae. The antigenic variability seen among different isolates has important implications for serologic tests and vaccine development. In the United States, most strains belong to the genomic group B burgdorferi sensu stricto, and in Europe most strains belong to the groups known as B garinii and B afzelii.
